Detalhe da pesquisa
1.
Targeted high-throughput mutagenesis of the human spliceosome reveals its in vivo operating principles.
Mol Cell
; 83(14): 2578-2594.e9, 2023 07 20.
Artigo
Inglês
| MEDLINE | ID: mdl-37402368
2.
Sequence-specific RNA recognition by an RGG motif connects U1 and U2 snRNP for spliceosome assembly.
Proc Natl Acad Sci U S A
; 119(6)2022 02 08.
Artigo
Inglês
| MEDLINE | ID: mdl-35101980
3.
Structural basis for DEAH-helicase activation by G-patch proteins.
Proc Natl Acad Sci U S A
; 117(13): 7159-7170, 2020 03 31.
Artigo
Inglês
| MEDLINE | ID: mdl-32179686
4.
Structural basis for the Nanos-mediated recruitment of the CCR4-NOT complex and translational repression.
Genes Dev
; 28(8): 888-901, 2014 Apr 15.
Artigo
Inglês
| MEDLINE | ID: mdl-24736845
5.
Biomolecular solid-state NMR spectroscopy at 1200 MHz: the gain in resolution.
J Biomol NMR
; 75(6-7): 255-272, 2021 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-34170475
6.
Regulation of DEAH-box RNA helicases by G-patch proteins.
Biol Chem
; 402(5): 561-579, 2021 04 27.
Artigo
Inglês
| MEDLINE | ID: mdl-33857358
7.
Towards a molecular understanding of microRNA-mediated gene silencing.
Nat Rev Genet
; 16(7): 421-33, 2015 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-26077373
8.
Evolutionary repurposing of a sulfatase: A new Michaelis complex leads to efficient transition state charge offset.
Proc Natl Acad Sci U S A
; 115(31): E7293-E7302, 2018 07 31.
Artigo
Inglês
| MEDLINE | ID: mdl-30012610
9.
The role of disordered protein regions in the assembly of decapping complexes and RNP granules.
Genes Dev
; 27(24): 2628-41, 2013 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-24352420
10.
The SMG5-SMG7 heterodimer directly recruits the CCR4-NOT deadenylase complex to mRNAs containing nonsense codons via interaction with POP2.
Genes Dev
; 27(19): 2125-38, 2013 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24115769
11.
An unusual arrangement of two 14-3-3-like domains in the SMG5-SMG7 heterodimer is required for efficient nonsense-mediated mRNA decay.
Genes Dev
; 27(2): 211-25, 2013 Jan 15.
Artigo
Inglês
| MEDLINE | ID: mdl-23348841
12.
Balancing Specificity and Promiscuity in Enzyme Evolution: Multidimensional Activity Transitions in the Alkaline Phosphatase Superfamily.
J Am Chem Soc
; 141(1): 370-387, 2019 01 09.
Artigo
Inglês
| MEDLINE | ID: mdl-30497259
13.
Human AATF/Che-1 forms a nucleolar protein complex with NGDN and NOL10 required for 40S ribosomal subunit synthesis.
Nucleic Acids Res
; 44(20): 9803-9820, 2016 Nov 16.
Artigo
Inglês
| MEDLINE | ID: mdl-27599843
14.
SMG6 interacts with the exon junction complex via two conserved EJC-binding motifs (EBMs) required for nonsense-mediated mRNA decay.
Genes Dev
; 24(21): 2440-50, 2010 Nov 01.
Artigo
Inglês
| MEDLINE | ID: mdl-20930030
15.
The activation of the decapping enzyme DCP2 by DCP1 occurs on the EDC4 scaffold and involves a conserved loop in DCP1.
Nucleic Acids Res
; 42(8): 5217-33, 2014 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-24510189
16.
Structure and properties of the esterase from non-LTR retrotransposons suggest a role for lipids in retrotransposition.
Nucleic Acids Res
; 41(22): 10563-72, 2013 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-24003030
17.
An efficient, multiply promiscuous hydrolase in the alkaline phosphatase superfamily.
Proc Natl Acad Sci U S A
; 107(7): 2740-5, 2010 Feb 16.
Artigo
Inglês
| MEDLINE | ID: mdl-20133613
18.
Take a break: Transcription regulation and RNA processing by the Integrator complex.
Curr Opin Struct Biol
; 77: 102443, 2022 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-36088798
19.
INTS10-INTS13-INTS14 form a functional module of Integrator that binds nucleic acids and the cleavage module.
Nat Commun
; 11(1): 3422, 2020 07 09.
Artigo
Inglês
| MEDLINE | ID: mdl-32647223
20.
USP16 counteracts mono-ubiquitination of RPS27a and promotes maturation of the 40S ribosomal subunit.
Elife
; 92020 03 04.
Artigo
Inglês
| MEDLINE | ID: mdl-32129764